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Journal / Biology / Heterotopic Heart Transplantation in Mice
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JoVE Journal Biology
Heterotopic Heart Transplantation in Mice
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Using Caenorhabditis elegans to Screen for Tissue-Specific Chaperone Interactions
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Heterotopic Heart Transplantation in Mice

Article DOI: 10.3791/238-v • 23:43 min • July 19th, 2007
July 19th, 2007 •
1, 1
1Department of Surgery, University of California, San Francisco - UCSF

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Summary
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The mouse heterotopic heart transplantation model has been proven by many investigators to be an important method for studying mechanisms of rejection and immune response. However, the techniques involved are still challenging. By modifying standard techniques we have had success with more than 1000 transplants.

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Heterotopic Heart Transplantation Mice Rejection Immune Response Transgenic Mice Gene Knockout Mice Immunologic Reagents Modified Technique Successful Cases Anastomosis Ascending Aorta Abdominal Aorta Pulmonary Artery Inferior Vena Cava
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