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Micropatterned表面透明质酸与肿瘤细胞相互作用的研究
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Bioengineering
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JoVE Journal Bioengineering
Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells
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Micropatterned表面透明质酸与肿瘤细胞相互作用的研究

DOI:
10.3791/2413-v

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10:13 min

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December 22, 2010

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1Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences Oncology Center and Institute for NanoBioTechnology,Johns Hopkins University

Chapters

  • 00:05Title
  • 01:33Standard Photolithography for Micropatterned Stamp Fabrication
  • 04:08Hyaluronic Acid Micropatterning
  • 07:57Cell Culture on HA Micropatterned Surfaces
  • 08:54Representative Results
  • 09:57Conclusion

Summary

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Automatic Translation

一种新颖的方法，使高分辨率的癌症细胞间的相互作用分析与外源性透明质酸（HA）的描述。图案的表面结构相结合的碳二亚胺化学和微接触印刷。

Tags

Micropatterned SurfacesHyaluronic AcidCancer CellsTumor MicroenvironmentECM ComponentsHA-CD44 InteractionTumor ProgressionCell MigrationMetastatic SpreadGlycosaminoglycanChemical ModificationsImmobilization Of HACell AdhesionFunctionalized SurfacesMicrocontact Printing (uCP)Cancer Cell Interactions

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