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JoVE Journal
Medicine

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Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction
 

Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction

Article doi: 10.3791/2581
June 7th, 2011

Summary June 7th, 2011

Numerous genetic manipulations and/or intramyocardial injections of genes, proteins, cells, and/or biomaterials are superimposed upon the dimension of time in studies of acute ischemia/ reperfusion injury and chronic remodeling in mice. This video illustrates the microsurgical procedures for ischemia/reperfusion, permanent coronary artery ligation, and intramyocardial injection studies.

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