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Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice
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Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice

Article DOI: 10.3791/2879 • 13:02 min • May 8th, 2011
May 8th, 2011 •
*1, *1,2, 1, 1, 1
1Department of Neurosurgery, University of Florida, 2Department of Anatomical Sciences, Shiraz University of Medical Sciences
* These authors contributed equally

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Summary
Automatic Translation

The intraluminal middle cerebral artery occlusion (MCAO) model is the most frequent used model among experimental ischemic stroke models. Here we will demonstrate the entire model in detail with the guide of Laser Doppler flowmetry, and its representative results.

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Intraluminal Middle Cerebral Artery Occlusion MCAO Model Ischemic Stroke Laser Doppler Flowmetry Guidance Mice Third Leading Cause Of Death Leading Cause Of Disability Cost United States Rat Modification Molecular Mechanisms Brain Injury Therapeutic Modalities Noninvasive Method Transgenic Strains Knockout Strains Focal Cerebral Ischemia Intraluminal Suture Internal Carotid Artery Base Of The MCA Spontaneous Reperfusion Permanent Retention Video Demonstration Drawbacks Pitfalls Ischemic Brain Tissue 2,3,5-triphenyltetrazolium Chloride (TTC) Cerebral Infarction
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