Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice

Saeed Ansari; Hassan Azari; Douglas J. McConnell; Aqeela Afzal; J Mocco

doi:10.3791/2879

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Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice

JoVE Journal
Medicine
Author Produced

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JoVE Journal Medicine

Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice

49,919 Views

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13:01 min

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May 08, 2011

DOI:

10.3791/2879-v

DOI:

10.3791/2879-v

•

13:01 min

May 08, 2011

•

31 Views

Saeed Ansari*¹, Hassan Azari*^1,2, Douglas J. McConnell¹, Aqeela Afzal¹, J Mocco¹

¹Department of Neurosurgery,University of Florida, ²Department of Anatomical Sciences,Shiraz University of Medical Sciences

Summary

The intraluminal middle cerebral artery occlusion (MCAO) model is the most frequent used model among experimental ischemic stroke models. Here we will demonstrate the entire model in detail with the guide of Laser Doppler flowmetry, and its representative results.