Journal
/
Bioengineering
/
Introduction to the Ultrasound Targeted Microbubble Destruction Technique
JoVE Journal
Bioengineering
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Bioengineering
Introduction to the Ultrasound Targeted Microbubble Destruction Technique

Introduction to the Ultrasound Targeted Microbubble Destruction Technique

DOI:
10.3791/2963-v

•

08:24 min

•

June 12, 2011

•

, , ,
1Department of Medicine, JABSOM,University of Hawaii

Chapters

  • 00:05Title
  • 01:44Microbubble Preparation
  • 02:48Equipment Calibration
  • 03:42Microbubble Delivery and UTMD
  • 06:23Bioluminescence Analysis of UTMD

Summary

Automatic Translation

Automatic Translation

Ultrasound Targeted Microbubble Destruction (UTMD) can be used to direct site-specific delivery of bioactive molecules, including therapeutic genes, to target organs accessible to ultrasound, such as the heart and liver1-6.

Tags

Ultrasound Targeted Microbubble Destruction TechniqueUTMDBioactive MoleculesPlasmid DNA VectorsLipid Microbubble Contrast AgentsAcoustic CavitationResonant FrequencySonoporation EffectTransfection EfficiencyEndothelial CellsTransgene-encoding VectorsSpecific Target-organ Transfection

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/2963?article_type=v

Contrast Ultrasound Targeted Treatment of Gliomas in Mice via Drug-Bearing Nanoparticle Delivery and Microvascular Ablation
check_url/2963?article_type=v

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
check_url/2963?article_type=v

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors
check_url/2963?article_type=v

Manufacture of Concentrated, Lipid-based Oxygen Microbubble Emulsions by High Shear Homogenization and Serial Concentration
check_url/2963?article_type=v

A Microfluidic Technique to Probe Cell Deformability
check_url/2963?article_type=v

A Microfluidic Chip for ICPMS Sample Introduction
check_url/2963?article_type=v

Synthesis of Gold Nanoparticle Integrated Photo-responsive Liposomes and Measurement of Their Microbubble Cavitation upon Pulse Laser Excitation
check_url/2963?article_type=v

An Experimental Protocol for Assessing the Performance of New Ultrasound Probes Based on CMUT Technology in Application to Brain Imaging
check_url/2963?article_type=v

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
check_url/2963?article_type=v

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Read Article