JoVE Encyclopedia of Experiments
Neuroscience
0 views • 6:21 min • May 29th, 2025
Position a patient with a chronic inner ear disorder, injected with an MRI contrast agent, in the MRI scanner.
Ensure that the patient’s head is straight and aligned with the isocenter of the MRI scanner.
Secure the head coil around the patient’s head to receive MRI signals.
Initiate the scan.
The scanner detects MR signals from the cranial nerves and fluid-filled areas of the inner ear.
The contrast agent accumulates in the fluid-filled spaces, making them appear brighter on the MRI images.
In contrast, the cranial nerves absorb only a small amount of contrast agent, appearing darker and enabling clear visualization.
Using medical imaging software, reconstruct the cranial nerve images.
Measure the cross-sectional area, long diameter, and short diameter of the nerves.
Compare these measurements with those of a healthy individual to identify abnormalities in cranial nerve morphology.
Begin by escorting the patient into the MRI room and having them lie on the scanner table. Be sure to position their head straight at the isocenter of the scanner and then secure the head coil.
Next, perform the MRI scan according to the study protocol, including 3D FLAIR and 3D Real IR sequences for detection of
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