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Chapters
- 00:05Title
- 01:04Frame and Clamp Design for Holding the Animal
- 01:32Surgery
- 02:46Spinal Cord Injury
- 04:48Behavioral and Histological Outcomes of Spinal Cord Injury
- 06:37Conclusion
A reliable and repeatable way to produce a cervical unilateral spinal cord injury using the Infinite Horizon impactor is described. The method takes advantage of a custom designed frame and clamp to stabilize the spine. The standardized procedure and biomechanical injury parameters result in sufficient and sustained injuries.
Tags
Contusive ModelUnilateral Cervical Spinal Cord InjuryInfinite Horizon ImpactorAnimal ModelsSpinal Cord InjuryThoracic Spinal CordBlunt TraumaNon-penetrating TraumaClinically Relevant Injury ModelsPreclinical EvaluationNovel TreatmentsContusion SCICervical Spinal CordTechnical AspectsAnatomical OutcomesBehavioral OutcomesLaminectomyImpact ForceImpact TrajectoryImpact LocationFunctional Recovery
