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Quantitative Comparison of cis-Regulatory Element (CRE) Activities in Transgenic Drosophila melanogaster
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Quantitative Comparison of cis-Regulatory Element (CRE) Activities in Transgenic Drosophila melanogaster

Article DOI: 10.3791/3395 • 08:19 min • December 19th, 2011
December 19th, 2011 •
1, 2
1Department of Biology, University of Dayton, 2Department of Biology, Center for Tissue Regeneration and Engineering at Dayton, University of Dayton

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Phenotypic variation for traits can result from mutations in cis-regulatory element (CRE) sequences that control gene expression patterns. Methods derived for use in Drosophila melanogaster can quantitatively compare the levels of spatial and temporal patterns of gene expression mediated by modified or naturally occurring CRE variants.

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Cis-regulatory Element CRE Activities Gene Expression Patterns Enhancers Cis-regulatory Modules Transcription Factor Proteins Regulatory Logic Development Program Morphological Evolution Genetic Variation Phenotypic Variation Reporter Transgenes In Vivo Function Heterologous Promoter Coding Sequences Reporter Gene Protein Product P-element Mediated Transgenesis Drosophila Melanogaster
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