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Germ Cell Transplantation and Testis Tissue Xenografting in Mice
 

Germ Cell Transplantation and Testis Tissue Xenografting in Mice

Article DOI: 10.3791/3545
February 6th, 2012

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Summary February 6th, 2012

Protocols for germ cell transplantation and testis tissue xenografting are described. Germ cell transplantation results in donor-derived spermatogenesis in recipient testes and represents a functional reconstitution assay for identification of spermatogonial stem cells (SSCs). Testis tissue xenografting reproduces testis development and spermatogenesis of various donor species in recipient mice.

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