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Immunology and Infection

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Induction of Graft-versus-host Disease and In Vivo T Cell Monitoring Using an MHC-matched Murine Model

Article DOI: 10.3791/3697 • 10:29 min
August 29th, 2012 •
1, 1
1Department of Surgery, The Ohio State University Medical Center

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August 29th, 2012

Murine bone marrow transplantation is a widely used technique to study immunological mechanisms governing graft-versus-host disease in humans. The ability to monitor T cell trafficking patterns in vivo allows for detailed analysis of the development and perpetuation of T cell responses during graft-versus-host disease.

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