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Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

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JoVE Journal Medicine

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

18,127 Views

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10:02 min

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May 02, 2012

DOI:

DOI:

•

10:02 min

May 02, 2012

•

1 Views

Nehal N. Mehta¹, Drew A. Torigian², Joel M. Gelfand³, Babak Saboury², Abass Alavi²

¹Division of Cardiovascular Medicine,University of Pennsylvania, Perelman School of Medicine, ²Department of Radiology,University of Pennsylvania, Perelman School of Medicine, ³Department of Dermatology,University of Pennsylvania, Perelman School of Medicine

Summary

There is great need to identify atherosclerosis non-invasively, and here we demonstrate how FDG-PET/CT can be used to detect and quantify atherosclerotic plaque activity and vascular inflammation.

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Atherosclerotic Plaque Activity Vascular Inflammation [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)Non-invasive Imaging Modalities Coronary Artery Calcium (CAC)Carotid Intimal Medial Thickness (C-IMT)Plaque Characteristics Plaque Composition Inflammatory State Clinical Events [18F]-2-fluoro-2-deoxy-D-glucose (FDG) Imaging Positron-emission Tomography (PET)/computed Tomography (CT)Macrophage Activity Cellular Inflammation Vessel Walls Inflammatory Activity Plaque Volume Metabolic Activity Multi-modal Atherosclerotic Plaque Quantification

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