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JoVE Journal
Bioengineering

This content is Open Access.

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
 

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery

Article doi: 10.3791/3876
April 17th, 2012

Summary April 17th, 2012

We developed a technology based on mesoporous silica thin film for the selective recovery of low molecular weight proteins and peptides from human serum. The physico-chemical properties of our mesoporous chips were finely tuned to provide substantial control in peptide enrichment and consequently profile the serum proteome for diagnostic purposes.

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