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JoVE Journal
Medicine

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NADH Fluorescence Imaging of Isolated Biventricular Working Rabbit Hearts
 

NADH Fluorescence Imaging of Isolated Biventricular Working Rabbit Hearts

Article DOI: 10.3791/4115
July 24th, 2012

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Summary July 24th, 2012

The objective is to monitor the mitochondrial redox state of isolated hearts within the context of physiologic preload and afterload pressures. A biventricular working rabbit heart model is presented. High spatiotemporal resolution fluorescence imaging of NADH is used to monitor the mitochondrial redox state of epicardial tissue.

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