An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

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Medicine

JoVE Journal
Medicine
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JoVE Journal Medicine

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

DOI:

10.3791/4207-v

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08:43 min

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July 28, 2012

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Moo Rim Kang*¹, Glen Yang*¹, Klaus Charisse, Hila Epstein-Barash, Muthiah Manoharan, Long-Cheng Li

¹Department of Urology and Helen Diller Comprehensive Cancer Center,University of California, San Francisco , ²Alnylam Pharmaceuticals, Inc.

Chapters

00:05Title
00:23Intravesical Tumor Cell Injection
04:00Bioluminescence Imaging
04:45Ultrasound Imaging
06:31Injection of saRNA
07:45Conclusion

Summary

Automatic Translation

Establishing an orthotopic bladder tumor model to evaluate antitumor effects of intravesically delivered saRNA and monitoring tumor growth by ultrasound and bioluminescent imaging.

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

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