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JoVE Journal
Immunology and Infection
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粒细胞相关的自身抗体引起的皮肤起泡
 
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粒细胞相关的自身抗体引起的皮肤起泡

Article DOI: 10.3791/4250
October 12th, 2012

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Summary October 12th, 2012

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在动物模型中描述在我们目前的工作中,纯化的IgG抗体对拉伸的200个氨基酸(氨基酸757-967)的胶原纤维VII反复被注入到小鼠体内,再现起泡表型以及直方和免疫病理学特征对人体acquisita大疱性表皮松解症(EBA)

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