50% Liver Resection

50% liver resection is a surgical procedure that removes approximately half of the liver while preserving enough functioning tissue to support essential metabolic and detoxification activities. During the operation, surgeons identify and divide the blood vessels and bile ducts supplying the targeted portion, remove the diseased or damaged tissue, and control bleeding before closing the remaining liver. The procedure may treat localized liver tumors, selected metastatic disease, or severe injury when preserving healthy tissue is feasible. Because the liver can restore volume and function after partial removal, postoperative monitoring focuses on liver performance, complications, and recovery.

50% Liver Resection - Related Videos

Research

JoVE Journal - Medicine

The Influence of Liver Resection on Intrahepatic Tumor Growth

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Cited by 6 •

2016

A high incidence of tumor recurrence after resection of liver metastases remains an unsolved problem. The illustrated mouse model may be useful to investigate the reasons for such recurrences. It combines a liver resection model with intrahepatic tumor cell injection for the first time.

Measuring the 50% Haemolytic Complement (CH50) Activity of Serum

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Cited by 92 •

2010

The classical pathway is activated by antibody and culminates in target cell lysis. The CH50 assay provides a measure of the complement activity of a serum sample. This video demonstrates the steps involved in determining the CH50 of a serum sample, the calculations and interpreting of results.

Brain Tumor Resection in a Mouse Using a Minimally Invasive Resection System

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2025

Source: Alomari, S., et al. Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection. J. Vis. Exp. (2022)This video demonstrates the use of a minimally invasive resection system (MIRS) to excise tumor tissue from an anesthetized mouse implanted with a tumor. The procedure involves securing the mouse onto a stereotactic frame, reopening the previous surgical site to access the brain, and inserting a specialized cannula that utilizes suction and a...

Research

JoVE Journal - Medicine
Free Sample

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

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2025

This protocol involves a laparoscopic anatomical resection of liver segment VII with liver parenchymal transection following a priority approach. This technique is unaffected by anatomical variations.

Decellularization and Recellularization of Whole Livers

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Cited by 39 •

2011

Perfusion decellularization is a novel technique to produce whole liver scaffolds that retains the organ's extracellular matrix composition and microarchitecture. Herein, the method of preparing whole organ scaffolds using perfusion decellularization and subsequent repopulation with hepatocytes is described. Functional and transplantable liver grafts can be generated using this technique.

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