Journal
/
Neuroscience
/
局部应用药物研究烟碱型乙酰胆碱受体功能的小鼠脑片
JoVE Journal
Neuroscience
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Neuroscience
Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices
Please note that all translations are automatically generated. Click here for the English version.

局部应用药物研究烟碱型乙酰胆碱受体功能的小鼠脑片

English

Automatically Generated

18,734 Views

•

10:04 min

•

October 29, 2012

DOI:

10.3791/50034-v

DOI:
10.3791/50034-v

•

10:04 min
October 29, 2012

•

6 Views
, ,
1Department of Medicinal Chemistry and Molecular Pharmacology,Purdue University

Summary

Automatically generated

在本文中，我们描述了一个有用的方法来研究神经元的急性分离的大脑切片配体门控离子通道的功能。这种方法涉及使用的药物填充微量移液器为本地应用程序使用标准的膜片钳技术记录神经元的药物。

Explore More Videos

Nicotinic Acetylcholine ReceptorNAChRNicotine AddictionElectrophysiologyWhole-cell Patch ClampBrain SlicesLocal Drug ApplicationNicotineAcetylcholineMouseNeuron

Read Article

Cite this Article

Engle, S. E., Broderick, H. J., Drenan, R. M. Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices. J. Vis. Exp. (68), e50034, doi:10.3791/50034 (2012).

Download .ris file

Copy

Share Video

.

Copy