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Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice
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JoVE Journal Medicine
Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice

Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice

DOI:
10.3791/50050-v

•

15:45 min

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February 10, 2013

•

, ,
1Instituto de Ciencias, Facultad de Medicina,Clínica Alemana Universidad del Desarrollo

Chapters

  • 00:02Title
  • 02:15Introduction
  • 02:57Preparing dobutamine infusion
  • 04:09Preparing pressure sensor
  • 05:22Preparing mouse for catheterization
  • 06:35Cardiac catheterization
  • 11:50Infusion of dobutamine
  • 12:48Data analysis
  • 13:31Representative results
  • 14:55Conclusion

Summary

Automatic Translation

Automatic Translation

We describe the protocol to perform a cardiac stress test induced by dobutamine and monitored by cardiac catheterization in normal mice. Also we show its application to unmask subclinical cardiac disease in high fat diet-induced obese mice.

Tags

Cardiac Stress TestDobutamineCardiac CatheterizationHemodynamic ParametersHeart RateSystolic PressureDiastolic PressureEnd-diastolic PressureDP/dtmaxDP/dtminObesityHigh-fat Diet

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