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Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
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Medicine
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JoVE Journal Medicine
Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR

DOI:
10.3791/50096-v

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07:24 min

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April 08, 2013

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, , ,
1Department of Surgery,UCSF/VA Medical Center, 2Clinical & Regulatory,LoneStar Heart, Inc.

Chapters

  • 00:05Title
  • 01:24Algisyl-LVR Implant Procedure
  • 03:00Digitization of the Left Ventricle
  • 04:15Quantification of Left Ventricular Stress Using Mathematical Modeling
  • 06:23Results: Injection of Algisyl-LVR Reduces Left Ventricular Wall Stress
  • 07:01Conclusion

Summary

Automatic Translation

Automatic Translation

This article describes procedures for implanting a novel hydrogel in failing hearts and quantifying its effect on left ventricular wall stress and function. These procedures have been successfully applied in dogs and humans.

Tags

Keywords: Algisyl-LVRDilated CardiomyopathyHeart FailureLeft Ventricular Wall StressLeft Ventricular FunctionMagnetic Resonance ImagingMathematical ModelingMyofiber StressCardiac FunctionIntramyocardial Injections

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