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JoVE Journal
Neuroscience

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Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue
 

Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue

Article DOI: 10.3791/50126
February 11th, 2013

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Summary February 11th, 2013

Here we present a histological method for capturing, labeling, optically clearing, and imaging the intact brain tissue interface around chronically implanted microdevices in rodent brain tissue. Results from the techniques comprising this method are useful for understanding the impact of various penetrating brain-implants on their surrounding tissue.

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