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2-Vessel Occlusion/Hypotension

2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia

Article DOI: 10.3791/50173
June 22nd, 2013


Summary June 22nd, 2013

Bilateral carotid occlusion coupled with systemic hypotension produces global brain ischemia in the rat, resulting in damage to the hippocampus with reproducible severity. Animal subjects are impaired with predictable patterns of brain damage, they recover expediently, and mortality rates are comparatively low.

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