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Journal / Behavior / Assessment of Sensorimotor Function in Mouse…
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Behavior

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JoVE Journal Behavior
Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease
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Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Article DOI: 10.3791/50303-v • 10:32 min • June 17th, 2013
June 17th, 2013 •
1,2, 1,2, 1
1Department of Psychology, University of Cincinnati, 2Department of Neurology, University of Cincinnati

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Summary
Automatic Translation

In Parkinson's disease and movement disorders in general, sensitive and reliable behavioral assays are essential for testing novel potential therapeutics. Here, we describe a manageable battery of sensorimotor tests for mice that are sensitive to varying degrees of injury to the nigrostriatal system and useful for preclinical studies.

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Sensorimotor Function Mouse Models Parkinson's Disease Behavioral Outcome Measures Therapeutic Treatments Preclinical Trials Neurodegenerative Diseases Nigrostriatal Dysfunction Sensorimotor Tests Efficacy Of Potential Therapeutics Genetic Mouse Models Of PD Battery Of Sensorimotor Tests Sensitivity Implementation Low Expense Disease-modifying Therapies
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