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JoVE Journal
Neuroscience

This content is Open Access.

Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System
 

Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System

Article DOI: 10.3791/50326
May 12th, 2013

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Summary May 12th, 2013

We describe a method to target drugs to the central nervous system by either implanting a catheter or performing a bolus injection into the right lateral ventricle in mice. We focus specifically on the delivery of antisense oligonucleotides. This technique is readily adaptable to other drugs and to rats.

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