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共聚焦成像在肝癌细胞中观察到的异常有丝分裂细胞死亡相关
JoVE Journal
Medicine
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JoVE Journal Medicine
Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells
DOI:

15:53 min

August 21, 2013

, , , , , ,

Chapters

  • 00:05Title
  • 02:07Preparation of Cells for Live Confocal Imaging
  • 05:02Examination of Transfection Efficacy
  • 06:42Preparation of Fixed Cells for Confocal Imaging
  • 09:20Results: PJ-34 Exhibits Cytotoxic Activity on Cells with Multi Centrosomes
  • 15:37Conclusion

Summary

Automatic Translation

菲PJ-34在肿瘤细胞进行有丝分裂的细胞毒活性,实时记录现场共聚焦成像。 PJ-34根除人类乳腺癌MDA-MB-231细胞有丝分裂窝藏额外中心体。额外中心体不像正常的双向焦点有丝分裂,不聚集在两个纺锤体的两极存在的PJ-34。

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