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JoVE Journal
Medicine

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Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
 

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Article doi: 10.3791/50627
May 26th, 2015

Summary May 26th, 2015

Ex vivo analysis of arterial lesions from animal models of cardiovascular disease classically relies on histological and immunohistochemical techniques. These provide 2-dimensional measurements in 3-dimensional lesions. This manuscript describes the generation of arterial lesions for quantitative analysis in 3-dimensions using optical projection tomography.

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