Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Generation and 3-Dimensional Quantitation of…
JoVE Journal
Medicine

This content is Open Access.

JoVE Journal Medicine
Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
Journal (Medicine)
Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
Journal (Medicine)
Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
 

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Article DOI: 10.3791/50627-v • 11:45 min • May 26th, 2015
May 26th, 2015 •
1, 1, 1, 1, 1, 1, 1, 1
1University/ BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute

Chapters

Summary
Automatic Translation

Ex vivo analysis of arterial lesions from animal models of cardiovascular disease classically relies on histological and immunohistochemical techniques. These provide 2-dimensional measurements in 3-dimensional lesions. This manuscript describes the generation of arterial lesions for quantitative analysis in 3-dimensions using optical projection tomography.

Tags

Generation 3-dimensional Quantitation Arterial Lesions Mice Optical Projection Tomography Cardiovascular Disease Research Lesion Formation Novel Therapies Atherosclerosis-prone Mice Surgical Methods Lesion Induction Dietary Modification Histological Techniques Non-destructive Analysis Immunohistochemical Analyses Neointimal Lesions Wire-insertion Ligation Femoral Artery Atherosclerotic Lesions Atherogenic Diet ApoE-deficient Mice OPT Imaging Autofluorescent Emission Histological Analysis Immunohistochemical Analysis Lesion Size Calculation
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter