JoVE Journal
Immunology and Infection
Immunology and Infection
A subscription to JoVE is required to view this content.
You will only be able to see the first 20 seconds.
Summary October 23rd, 2013
We describe a methodology to perform genetic analysis in Chlamydia based on chemical mutagenesis and whole genome sequencing. In addition, a system for DNA exchange within infected cells is described that can be used for genetic mapping. This method may be broadly applicable to microbial systems lacking transformation systems and molecular genetic tools.
