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表皮黑色素和防止晒斑的人性化小鼠模型的诱导药物
JoVE Journal
Medicine
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JoVE Journal Medicine
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
DOI:

12:37 min

September 07, 2013

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Chapters

  • 00:05Title
  • 02:12Preparation of C57Bl/6 K14-Scf Mice and Topical Forskolin Treatment
  • 04:31Reflective Colorimetry and Calculating the Minimal Erythematous Dose
  • 08:15Representative Melanin Induction Results
  • 11:43Conclusion

Summary

Automatic Translation

表皮黑色素是由毛喉素局部应用在皮肤白皙的紫外线敏感的人小鼠模型诱导。 cAMP水平的皮肤和表皮发黑免受紫外线介导的炎症(晒斑)强烈保护如由最小红斑量(MED)法测定的药理操纵。

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