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JoVE Journal
Immunology and Infection

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In vivo Imaging Method to Distinguish Acute and Chronic Inflammation
 

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

Article DOI: 10.3791/50690
August 16th, 2013

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Summary August 16th, 2013

We describe a non-invasive imaging method for distinguishing inflammatory stages. Systemic delivery of luminol reveals areas of acute inflammation dependent upon MPO activity in neutrophils. In contrast, injection of lucigenin allows for visualization of chronic inflammation dependent upon Phox activity in macrophages.

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