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In vivo Imaging Method to Distinguish Acute and Chronic Inflammation
<em>In vivo</em> Imaging Method to Distinguish Acute and Chronic Inflammation
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

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07:10 min

August 16, 2013

DOI:

07:10 min
August 16, 2013

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Summary

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We describe a non-invasive imaging method for distinguishing inflammatory stages. Systemic delivery of luminol reveals areas of acute inflammation dependent upon MPO activity in neutrophils. In contrast, injection of lucigenin allows for visualization of chronic inflammation dependent upon Phox activity in macrophages.

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