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Biology

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Confocal Imaging of Single Mitochondrial Superoxide Flashes in Intact Heart or In Vivo
 

Confocal Imaging of Single Mitochondrial Superoxide Flashes in Intact Heart or In Vivo

Article doi: 10.3791/50818
November 5th, 2013

Summary November 5th, 2013

Confocal scanning microscopy is applied for imaging single mitochondrial events in perfused heart or skeletal muscles in live animal. Real-time monitoring of single mitochondrial processes such as superoxide flashes and membrane potential fluctuations enables the evaluation of mitochondrial function in a physiologically relevant context and during pathological perturbations.

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