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JoVE Journal
Immunology and Infection

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Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species
 

Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Article DOI: 10.3791/50853
November 6th, 2013

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Summary November 6th, 2013

Scavengers have potential to translocate infectious transmissible spongiform encephalopathy prions in their feces to disease-free areas. We detail methods used to determine if mouse-adapted scrapie prions remain infectious after passage though the digestive tract of American crows (Corvus brachyrhynchos), a common consumer of dead animals.

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