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Journal / Immunology and Infection / Mielina Oligodendrocyte glicoproteina (MOG
JoVE Journal
Immunology and Infection

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Mielina Oligodendrocyte glicoproteina (MOG

Article DOI: 10.3791/51275-v • 08:03 min • April 15th, 2014
April 15th, 2014 •
1,2, 1, 1, 1,3
1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology, University of Münster

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Encefalomielite autoimmune sperimentale (EAE) è un modello animale di sclerosi multipla. C57BL / 6 topi sono immunizzati con mielina oligodendrociti glicoproteina (MOG) peptide 35-55 (MOG 35-55), con un conseguente paralisi flaccida ascendente causata da cellule immunitarie autoreattive nel sistema nervoso centrale. Saranno discussi protocolli per l'induzione della malattia e monitoraggio.

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Immunologia Numero 86 l'encefalomielite autoimmune sperimentale EAE sclerosi multipla MS modello animale autoimmunità neuroinflammation sistema nervoso centrale pertosse
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