Heinz Wiendl

Department of Neurology, University of Münster

Affiliated withUniversity of Münster University Hospital Münster

Research Area

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 169	2014
Publication title Cited by 3	2015
Publication title Cited by 12	2016
Publication title Cited by 6	2017

Other Publications

Article	Year
Comment on "Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse". Immunology letters\| PubMed ID: 19595706	2009
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Science advances\| PubMed ID: 27386562	2016
Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis. Annals of neurology\| PubMed ID: 11891826	2002
A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11971028	2002
An autoreactive gamma delta TCR derived from a polymyositis lesion. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12077283	2002
Advances in pathogenic concepts and therapeutic agents in Rasmussen's encephalitis. Expert opinion on investigational drugs\| PubMed ID: 12084008	2002
Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 12102646	2002
The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy. Brain : a journal of neurology\| PubMed ID: 12477705	2003
Acute transverse myelitis associated with coxiella burnetii infection. Journal of neurology\| PubMed ID: 12532936	2002
Disease-modifying therapies in multiple sclerosis: an update on recent and ongoing trials and future strategies. Expert opinion on investigational drugs\| PubMed ID: 12665424	2003
Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies. Brain : a journal of neurology\| PubMed ID: 12690043	2003
Human herpesvirus 6 in serum and spinal fluid of patients with multiple sclerosis? Archives of neurology\| PubMed ID: 12707085	2003
Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies. Journal of neuroimmunology\| PubMed ID: 12742663	2003
The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis. Journal of neuroimmunology\| PubMed ID: 12864987	2003
Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory ... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12923066	2003
Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes. Journal of neuroimmunology\| PubMed ID: 14597095	2003
Express and protect yourself: the potential role of HLA-G on muscle cells and in inflammatory myopathies. Human immunology\| PubMed ID: 14602235	2003
Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo. Glia\| PubMed ID: 14603470	2003
Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis. Cancer research\| PubMed ID: 14612546	2003
Modulation of neuronal activity by the endogenous pentapeptide QYNAD. The European journal of neuroscience\| PubMed ID: 14656318	2003
A novel homozygous missense mutation in the GNE gene of a patient with quadriceps-sparing hereditary inclusion body myopathy associated with muscle inflammation. Neuromuscular disorders : NMD\| PubMed ID: 14678807	2003
Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells. Seminars in cancer biology\| PubMed ID: 14708714	2003
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15100291	2004
Antigen recognition properties of a Vgamma1.3Vdelta2-T-cell receptor from a rare variant of polymyositis. Journal of neuroimmunology\| PubMed ID: 15223249	2004
Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple s... Journal of neuroimmunology\| PubMed ID: 15342209	2004
Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclero... Journal of neuroimmunology\| PubMed ID: 15652415	2005
Diffusion abnormality in Balo's concentric sclerosis: clues for the pathogenesis. European neurology\| PubMed ID: 15746544	2005
Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells. Experimental cell research\| PubMed ID: 15748884	2005
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15758163	2005
Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system. Journal of neuroimmunology\| PubMed ID: 15833357	2005
A PD-1 polymorphism is associated with disease progression in multiple sclerosis. Annals of neurology\| PubMed ID: 15912506	2005
Immunobiology of muscle: advances in understanding an immunological microenvironment. Trends in immunology\| PubMed ID: 15922662	2005
Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity. Brain : a journal of neurology\| PubMed ID: 16123145	2005
Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro. Journal of neuroimmunology\| PubMed ID: 16171875	2005
Muscle-derived positive and negative regulators of the immune response. Current opinion in rheumatology\| PubMed ID: 16224248	2005
Acute disseminated encephalomyelitis: an update. Archives of neurology\| PubMed ID: 16286539	2005
Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D-li... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16293707	2006
Multiple sclerosis: advances, excitements, disenchantments. Lancet neurology\| PubMed ID: 16361006	2006
The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons. Molecular pharmacology\| PubMed ID: 16424077	2006
Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro. International journal of cancer. Journal international du cancer\| PubMed ID: 16482562	2006
No effect of immunomodulatory therapy in focal epilepsy with positive glutamate receptor type 3--antibodies. Seizure : the journal of the British Epilepsy Association\| PubMed ID: 16621617	2006
The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans. Experimental hematology\| PubMed ID: 16797416	2006
Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation. Experimental neurology\| PubMed ID: 16814281	2006
Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16885234	2006
The inflamed peripheral nervous system: update on immune therapies. Current opinion in neurology\| PubMed ID: 16969151	2006
Immune circuitry in the peripheral nervous system. Current opinion in neurology\| PubMed ID: 16969152	2006
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies. Neurobiology of disease\| PubMed ID: 17207628	2007
HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation. Blood\| PubMed ID: 17371944	2007
HLA-G in the nervous system. Human immunology\| PubMed ID: 17400065	2007
Treatment of active secondary progressive multiple sclerosis with treosulfan. Journal of neurology\| PubMed ID: 17446994	2007
The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis. Human immunology\| PubMed ID: 17462509	2007
Treatment and treatment trials in multiple sclerosis. Current opinion in neurology\| PubMed ID: 17495622	2007
Oral disease-modifying treatments for multiple sclerosis: the story so far. CNS drugs\| PubMed ID: 17521228	2007
WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism? Acta neuropathologica\| PubMed ID: 17541610	2007
Modulation of T-effector function by imatinib at the level of cytokine secretion. Experimental hematology\| PubMed ID: 17560008	2007
Postpartum-activation of multiple sclerosis is associated with down-regulation of tolerogenic HLA-G. Journal of neuroimmunology\| PubMed ID: 17561269	2007
Immune-refractory cancers and their little helpers--an extended role for immunetolerogenic MHC molecules HLA-G and HLA-E? Seminars in cancer biology\| PubMed ID: 17768067	2007
Multiple sclerosis therapy: an update on recently finished trials. Journal of neurology\| PubMed ID: 18004638	2007
Pharmacological treatment of early multiple sclerosis. Drugs\| PubMed ID: 18081373	2008
CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing. Journal of neuroimmunology\| PubMed ID: 18164423	2008
The two-pore domain potassium channel TASK3 functionally impacts glioma cell death. Journal of neuro-oncology\| PubMed ID: 18217213	2008
TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions. The Journal of biological chemistry\| PubMed ID: 18375952	2008
B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. European journal of immunology\| PubMed ID: 18421793	2008
Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18490751	2008
The role of regulatory T cells in multiple sclerosis. Nature clinical practice. Neurology\| PubMed ID: 18578001	2008
The metalloproteinase-disintegrin ADAM10 is exclusively expressed by type I muscle fibers. Muscle & nerve\| PubMed ID: 18642355	2008
Human myoblasts modulate the function of antigen-presenting cells. Journal of neuroimmunology\| PubMed ID: 18644633	2008
The role of CD8 suppressors versus destructors in autoimmune central nervous system inflammation. Human immunology\| PubMed ID: 18723060	2008
A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis. PloS one\| PubMed ID: 18773080	2008
The trials and errors in MS therapy. International MS journal / MS Forum\| PubMed ID: 18808741	2008
Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation. Neuroscience letters\| PubMed ID: 18824070	2008
Effects of natalizumab treatment on Foxp3+ T regulatory cells. PloS one\| PubMed ID: 18836525	2008
The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. Neurobiology of disease\| PubMed ID: 18930826	2009
Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions. Arthritis and rheumatism\| PubMed ID: 18975328	2008
The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy. Neurobiology of disease\| PubMed ID: 18996482	2009
Idiopathic inflammatory myopathies: current and future therapeutic options. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 19019306	2008
Intracerebral dendritic cells critically modulate encephalitogenic versus regulatory immune responses in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19129392	2009
Frequency of regulatory T cells is not affected by transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis. The open rheumatology journal\| PubMed ID: 19156222	2008
CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery. Brain : a journal of neurology\| PubMed ID: 19179379	2009
PD-1 regulates neural damage in oligodendroglia-induced inflammation. PloS one\| PubMed ID: 19197390	2009
Intercellular exchanges of membrane fragments (trogocytosis) between human muscle cells and immune cells: a potential mechanism for the modulation of muscular immune responses. Journal of neuroimmunology\| PubMed ID: 19269695	2009
Multiple sclerosis therapeutics: unexpected outcomes clouding undisputed successes. Neurology\| PubMed ID: 19289741	2009
Immunomodulatory treatment strategies in multiple sclerosis. Journal of neurology\| PubMed ID: 19300955	2008
Recent clinical trials and future therapies. Journal of neurology\| PubMed ID: 19300967	2008
T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible. Journal of leukocyte biology\| PubMed ID: 19401389	2009
Antigen-specific blockade of lethal CD8 T-cell mediated autoimmunity in a mouse model of multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19414812	2009
The level of B7 homologue 1 expression on brain DC is decisive for CD8 Treg cell recruitment into the CNS during EAE. European journal of immunology\| PubMed ID: 19424967	2009
Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants. The American journal of pathology\| PubMed ID: 19443704	2009
Expression of antigen processing and presenting molecules by Schwann cells in inflammatory neuropathies. Glia\| PubMed ID: 19544394	2010
CD8+ T cells and neuronal damage: direct and collateral mechanisms of cytotoxicity and impaired electrical excitability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 19567369	2009
TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. Brain : a journal of neurology\| PubMed ID: 19570851	2009
Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss. The American journal of pathology\| PubMed ID: 19700745	2009
Specific central nervous system recruitment of HLA-G(+) regulatory T cells in multiple sclerosis. Annals of neurology\| PubMed ID: 19705413	2009
Current status on B-cell depletion therapy in autoimmune diseases other than rheumatoid arthritis. Autoimmunity reviews\| PubMed ID: 19716441	2009
The future of multiple sclerosis therapy. Pharmacological research : the official journal of the Italian Pharmacological Society\| PubMed ID: 19717009	2009
Iatrogenic immunosuppression with biologics in MS: expecting the unexpected? Neurology\| PubMed ID: 19776376	2009
Collateral neuronal apoptosis in CNS gray matter during an oligodendrocyte-directed CD8(+) T cell attack. Glia\| PubMed ID: 19780193	2010
Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation. Neurobiology of disease\| PubMed ID: 19914379	2010
Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20007464	2009
Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20028655	2010
Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve. Experimental neurology\| PubMed ID: 20051242	2010
Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A. Neurobiology of disease\| PubMed ID: 20064611	2010
Active immunization induces toxicity of diphtheria toxin in diphtheria resistant mice--implications for neuroinflammatory models. Journal of immunological methods\| PubMed ID: 20138048	2010
Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation. Blood\| PubMed ID: 20215643	2010
The role of dendritic cells in CNS autoimmunity. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 20217033	2010
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain : a journal of neurology\| PubMed ID: 20354004	2010
An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20357264	2010
Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis. Brain, behavior, and immunity\| PubMed ID: 20385225	2010
B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells. PloS one\| PubMed ID: 20520738	2010
From the background to the spotlight: TASK channels in pathological conditions. Brain pathology (Zurich, Switzerland)\| PubMed ID: 20529081	2010
FOXP3+ T regulatory cells in idiopathic inflammatory myopathies. Journal of neuroimmunology\| PubMed ID: 20537411	2010
Upregulation of K2P5.1 potassium channels in multiple sclerosis. Annals of neurology\| PubMed ID: 20582984	2010
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of immunomodulatory treatment strategies. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 20623991	2010
Natalizumab treatment in a patient with chronic inflammatory demyelinating polyneuropathy. Archives of neurology\| PubMed ID: 20625098	2010
Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9). Experimental & translational stroke medicine\| PubMed ID: 20646278	2010
Postpartum disease activity and breastfeeding in multiple sclerosis revisited. Neurology\| PubMed ID: 20679632	2010
Identification of targets and new developments in the treatment of multiple sclerosis--focus on cladribine. Drug design, development and therapy\| PubMed ID: 20689698	2010
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 20795753	2010
Glatiramer acetate attenuates pro-inflammatory T cell responses but does not directly protect neurons from inflammatory cell death. The American journal of pathology\| PubMed ID: 21037084	2010
CD34+ progenitor cells mobilized by natalizumab are not a relevant reservoir for JC virus. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21078695	2011
Temporal pattern of ICAM-I mediated regulatory T cell recruitment to sites of inflammation in adoptive transfer model of multiple sclerosis. PloS one\| PubMed ID: 21085578	2010
Janus head: the dual role of HLA-G in CNS immunity. Cellular and molecular life sciences : CMLS\| PubMed ID: 21086150	2011
Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis. European journal of immunology\| PubMed ID: 21108477	2010
Natalizumab restores evoked potential abnormalities in patients with relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21135021	2011
Active immunization with proteolipid protein (190-209) induces ascending paralysing experimental autoimmune encephalomyelitis in C3H/HeJ mice. Journal of immunological methods\| PubMed ID: 21199659	2011
Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking. Journal of autoimmunity\| PubMed ID: 21216565	2011
Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients. Arthritis research & therapy\| PubMed ID: 21314928	2011
Risks and benefits of multiple sclerosis therapies: need for continual assessment? Current opinion in neurology\| PubMed ID: 21483261	2011
Ion channels in autoimmune neurodegeneration. FEBS letters\| PubMed ID: 21501610	2011
Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders. PloS one\| PubMed ID: 21533133	2011
Immune mechanisms of new therapeutic strategies in multiple sclerosis-A focus on alemtuzumab. Clinical immunology (Orlando, Fla.)\| PubMed ID: 21550857	2012
Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID). Arthritis research & therapy\| PubMed ID: 21569519	2011
Transforming multiple sclerosis trials into practical reality. Lancet neurology\| PubMed ID: 21571592	2011
Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels. Biochimica et biophysica acta\| PubMed ID: 21575593	2011
Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice. Therapeutic advances in neurological disorders\| PubMed ID: 21694816	2011
Immunological and clinical consequences of treating a patient with natalizumab. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21908480	2012
Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy. Acta neuropathologica\| PubMed ID: 22057786	2012
Rapidly progressive B-cell dominated inflammatory neuropathy and littoral cell angioma of the spleen associated with plasmablastic B-cell lymphoma. Leukemia & lymphoma\| PubMed ID: 22098375	2012
IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22116823	2012
Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. Nature neuroscience\| PubMed ID: 22138643	2012
CD4(+) T cells predominate in cerebrospinal fluid and leptomeningeal and parenchymal infiltrates in cerebral amyloid β-related angiitis. Archives of neurology\| PubMed ID: 22351850	2012
CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenc... Journal of neuroinflammation\| PubMed ID: 22373353	2012
Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ. Brain : a journal of neurology\| PubMed ID: 22447120	2012
Neuron-directed autoimmunity in the central nervous system: entities, mechanisms, diagnostic clues, and therapeutic options. Current opinion in neurology\| PubMed ID: 22487567	2012
Neuroinflammation: the world is not enough. Current opinion in neurology\| PubMed ID: 22487569	2012
Fulfilling the dream: tolerogenic dendritic cells to treat multiple sclerosis. European journal of immunology\| PubMed ID: 22488360	2012
Immune mechanisms of stroke. Current opinion in neurology\| PubMed ID: 22547104	2012
Immune therapy of multiple sclerosis--future strategies. Current pharmaceutical design\| PubMed ID: 22612746	2012
Anti-JC-virus antibody prevalence in a German MS cohort. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22740609	2012
Cytotoxic CD8+ T cells and CD138+ plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies. Journal of neuroinflammation\| PubMed ID: 22759321	2012
Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells. Immunity\| PubMed ID: 22902234	2012
The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis. Experimental neurology\| PubMed ID: 22960185	2012
Paraneoplastic and non-paraneoplastic autoimmunity to neurons in the central nervous system. Journal of neurology\| PubMed ID: 22983427	2013
Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes. Biochimica et biophysica acta\| PubMed ID: 23041580	2013
TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation. PloS one\| PubMed ID: 23077651	2012
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood\| PubMed ID: 23160472	2013
Clinical effects of natalizumab on multiple sclerosis appear early in treatment course. Journal of neurology\| PubMed ID: 23292204	2013
Multiple sclerosis: reprogramming the immune repertoire with alemtuzumab in MS. Nature reviews. Neurology\| PubMed ID: 23358486	2013
Dendritic cell vaccination in autoimmune disease. Current opinion in rheumatology\| PubMed ID: 23370378	2013
Correction: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9). Experimental & translational stroke medicine\| PubMed ID: 23374257	2013
An assay to quantify species-specific anti-JC virus antibody levels in MS patients. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23388163	2013
Thalamic involvement in patients with neurologic impairment due to Shiga toxin 2. Annals of neurology\| PubMed ID: 23424019	2013
Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23459571	2013
Neurons as targets for T cells in the nervous system. Trends in neurosciences\| PubMed ID: 23478065	2013
Monoclonal antibodies in neuroinflammatory diseases. Expert opinion on biological therapy\| PubMed ID: 23521026	2013
Interferon beta use and disability prevention in relapsing-remitting multiple sclerosis. JAMA neurology\| PubMed ID: 23530268	2013
Fine-tuning of regulatory T cell function: the role of calcium signals and naive regulatory T cells for regulatory T cell deficiency in multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23576680	2013
Modulation of IL-2Rα with daclizumab for treatment of multiple sclerosis. Nature reviews. Neurology\| PubMed ID: 23732529	2013
4-Aminopyridine ameliorates mobility but not disease course in an animal model of multiple sclerosis. Experimental neurology\| PubMed ID: 23748135	2013
Rasmussen encephalitis treated with natalizumab. Neurology\| PubMed ID: 23794679	2013
Con: Regulatory T cells are protective in ischemic stroke. Stroke; a journal of cerebral circulation\| PubMed ID: 23821227	2013
L-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients. Neurology\| PubMed ID: 23925765	2013
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS. Nature medicine\| PubMed ID: 23933981	2013
Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter. Journal of neuroinflammation\| PubMed ID: 24093512	2013
Identification of inflammatory neuronal injury and prevention of neuronal damage in multiple sclerosis: hope for novel therapies? JAMA neurology\| PubMed ID: 24145957	2013
Kinetics of IL-6 production defines T effector cell responsiveness to regulatory T cells in multiple sclerosis. PloS one\| PubMed ID: 24155968	2013
DTI detects water diffusion abnormalities in the thalamus that correlate with an extremity pain episode in a patient with multiple sclerosis. NeuroImage. Clinical\| PubMed ID: 24179780	2013
Correction: Kinetics of IL-6 Production Defines T Effector Cell Responsiveness to Regulatory T Cells in Multiple Sclerosis. PloS one\| PubMed ID: 24282490	2013
CD4+NKG2D+ T cells exhibit enhanced migratory and encephalitogenic properties in neuroinflammation. PloS one\| PubMed ID: 24282598	2013
Evans syndrome associated with sterile inflammation of the central nervous system: a case report. Journal of medical case reports\| PubMed ID: 24299473	2013
Specific loss of cellular L-selectin on CD4+ T cells is associated with PML development during HIV infection. AIDS (London, England)\| PubMed ID: 24445368	2014
Clinical relevance of brain volume measures in multiple sclerosis. CNS drugs\| PubMed ID: 24446248	2014
New evidence for teriflunomide in multiple sclerosis. Lancet neurology\| PubMed ID: 24461573	2014
Efficacy and safety of natalizumab in multiple sclerosis: interim observational programme results. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 24532785	2014
Specific aspects of modern life for people with multiple sclerosis: considerations for the practitioner. Therapeutic advances in neurological disorders\| PubMed ID: 24587828	2014
The neuroinflammation biobank in the department of neurology, university hospital muenster, Germany. Biopreservation and biobanking\| PubMed ID: 24620773	2014
Programmed Cell Death-1 Deficiency Exacerbates T Cell Activation and Atherogenesis despite Expansion of Regulatory T Cells in Atherosclerosis-Prone Mice. PloS one\| PubMed ID: 24691202	2014
Teriflunomide and its mechanism of action in multiple sclerosis. Drugs\| PubMed ID: 24740824	2014
Blocking of α4 integrin does not protect from acute ischemic stroke in mice. Stroke; a journal of cerebral circulation\| PubMed ID: 24743435	2014
Human CD4+ HLA-G+ regulatory T cells are potent suppressors of graft-versus-host disease in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24744146	2014
Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity. Annals of neurology\| PubMed ID: 24771567	2014
Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. European journal of immunology\| PubMed ID: 24811005	2014
Immunophenotyping of cerebrospinal fluid cells in multiple sclerosis: in search of biomarkers. JAMA neurology\| PubMed ID: 24818670	2014
Effects of glatiramer acetate in a spontaneous model of autoimmune neuroinflammation. The American journal of pathology\| PubMed ID: 24819960	2014
Response to letter regarding article, "blocking of α4 integrin does not protect from acute ischemic stroke in mice". Stroke\| PubMed ID: 25061081	2014
VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. The Journal of experimental medicine\| PubMed ID: 25135296	2014
Facing the challenges of chronic pruritus: a report from a multi-disciplinary medical itch centre in Germany. Acta dermato-venereologica\| PubMed ID: 25136974	2015
Apraxia profile differentiates behavioural variant frontotemporal from Alzheimer's dementia in mild disease stages. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 25248366	2015
Clinical relevance of specific T-cell activation in the blood and cerebrospinal fluid of patients with mild Alzheimer's disease. Neurobiology of aging\| PubMed ID: 25277040	2015
FoxP3+ regulatory T cells determine disease severity in rodent models of inflammatory neuropathies. PloS one\| PubMed ID: 25286182	2014
CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25315859	2015
Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis. International immunology\| PubMed ID: 25326459	2015
CD3-positive B cells: a storage-dependent phenomenon. PloS one\| PubMed ID: 25329048	2014
Immunotherapy of multiple sclerosis. Acta neuropsychiatrica\| PubMed ID: 25384864	2009
Effects of blood transportation on human peripheral mononuclear cell yield, phenotype and function: implications for immune cell biobanking. PloS one\| PubMed ID: 25541968	2014
Long-term efficacy of alemtuzumab in polymyositis. Rheumatology (Oxford, England)\| PubMed ID: 25552256	2014
Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25583847	2015
A human post-mortem brain model for the standardization of multi-centre MRI studies. NeuroImage\| PubMed ID: 25595502	2015
Increased cortical curvature reflects white matter atrophy in individual patients with early multiple sclerosis. NeuroImage. Clinical\| PubMed ID: 25610761	2014
FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25732840	2015
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Comparative efficacy of switching to natalizumab in active multiple sclerosis. Annals of clinical and translational neurology\| PubMed ID: 25909083	2015
Evidence for early, non-lesional cerebellar damage in patients with multiple sclerosis: DTI measures correlate with disability, atrophy, and disease duration. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25921041	2016
Switching from natalizumab to fingolimod: A randomized, placebo-controlled study in RRMS. Neurology\| PubMed ID: 26024899	2015
Pharmacological Approaches to Delaying Disability Progression in Patients with Multiple Sclerosis. Drugs\| PubMed ID: 26033077	2015
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Nrf2 and beyond: deciphering the mode of action of fumarates in the inflamed central nervous system. Acta neuropathologica\| PubMed ID: 26123982	2015
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Trafficking of lymphocytes into the CNS. Oncotarget\| PubMed ID: 26255669	2015
Treating a GAD65 Antibody-Associated Limbic Encephalitis with Basiliximab: A Case Study. Frontiers in neurology\| PubMed ID: 26284025	2015
A novel automated segmentation method for retinal layers in OCT images proves retinal degeneration after optic neuritis. The British journal of ophthalmology\| PubMed ID: 26307452	2016
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Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis. The New England journal of medicine\| PubMed ID: 26444729	2015
Implications of dietary salt intake for multiple sclerosis pathogenesis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26447064	2016
Dementia Apraxia Test (DATE): A Brief Tool to Differentiate Behavioral Variant Frontotemporal Dementia from Alzheimer's Dementia Based on Apraxia Profiles. Journal of Alzheimer's disease : JAD\| PubMed ID: 26484911	2016
Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array. Genetic epidemiology\| PubMed ID: 26497834	2015
Case report of bilateral relapsing-remitting sciatic nerve palsy during two pregnancies. BMC research notes\| PubMed ID: 26545719	2015
Neuroimmunotherapies Targeting T Cells: From Pathophysiology to Therapeutic Applications. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 26563391	2016
CD4+ T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients. Neuro-oncology\| PubMed ID: 26578623	2016
Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity. Journal of autoimmunity\| PubMed ID: 26584738	2016
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Impaired Autonomic Responses to Emotional Stimuli in Autoimmune Limbic Encephalitis. Frontiers in neurology\| PubMed ID: 26648907	2015
Highlights from the 31st ECTRIMS congress - Barcelona 2015. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26684283	2016
Dimethyl fumarate treatment alters circulating T helper cell subsets in multiple sclerosis. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 26767188	2016
Epoch Analysis of On-Treatment Disability Progression Events over Time in the Tysabri Observational Program (TOP). PloS one\| PubMed ID: 26771747	2016
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Early silent microstructural degeneration and atrophy of the thalamocortical network in multiple sclerosis. Human brain mapping\| PubMed ID: 26920497	2016
ALAIN01--Alemtuzumab in autoimmune inflammatory neurodegeneration: mechanisms of action and neuroprotective potential. BMC neurology\| PubMed ID: 26966029	2016
Guidelines on dermatomyositis--excerpt from the interdisciplinary S2k guidelines on myositis syndromes by the German Society of Neurology. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG\| PubMed ID: 26972210	2016
Immunoadsorption therapy in autoimmune encephalitides. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 26977423	2016
Simultaneous early-onset immune thrombocytopenia and autoimmune thyroid disease following alemtuzumab treatment in relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26980848	2016
CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing. Nature communications\| PubMed ID: 27040081	2016
Failed, interrupted and inconclusive trials on relapsing multiple sclerosis treatment: update 2010-2015. Expert review of neurotherapeutics\| PubMed ID: 27058174	2016
Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS. Neurology. Clinical practice\| PubMed ID: 27104064	2016
Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27162345	2016
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nature communications\| PubMed ID: 27188843	2016
Evidence of a pathogenic role for CD8(+) T cells in anti-GABAB receptor limbic encephalitis. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 27213174	2016
The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion. Acta neuropathologica\| PubMed ID: 27383204	2016
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The potassium channels TASK2 and TREK1 regulate functional differentiation of murine skeletal muscle cells. American journal of physiology. Cell physiology\| PubMed ID: 27488672	2016
The quality of cortical network function recovery depends on localization and degree of axonal demyelination. Brain, behavior, and immunity\| PubMed ID: 27569659	2016
CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients. Neurology\| PubMed ID: 27572431	2016
Shared neural correlates of limb apraxia in early stages of Alzheimer's dementia and behavioural variant frontotemporal dementia. Cortex; a journal devoted to the study of the nervous system and behavior\| PubMed ID: 27639684	2016
B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27671636	2016
Dichoptic Metacontrast Masking Functions to Infer Transmission Delay in Optic Neuritis. PloS one\| PubMed ID: 27711139	2016
14-3-3 Proteins regulate K2P 5.1 surface expression on T lymphocytes. Traffic (Copenhagen, Denmark)\| PubMed ID: 27743426	2016
Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 27766281	2016
Prothrombin and factor X are elevated in multiple sclerosis patients. Annals of neurology\| PubMed ID: 27774643	2016
Acute cholecystitis during treatment with alemtuzumab in 3 patients with RRMS. Neurology\| PubMed ID: 27794114	2016
Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease. Science translational medicine\| PubMed ID: 27797962	2016
CD62L test at 2 years of natalizumab predicts progressive multifocal leukoencephalopathy. Neurology\| PubMed ID: 27815407	2016
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier. Science translational medicine\| PubMed ID: 27831901	2016
Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 27957508	2017
Computed tomography-based quantification of lesion water uptake identifies patients within 4.5 hours of stroke onset: A multicenter observational study. Annals of neurology\| PubMed ID: 28001316	2016
Regulatory Functions of Natural Killer Cells in Multiple Sclerosis. Frontiers in immunology\| PubMed ID: 28066417	2016
Diagnostic criteria for Susac syndrome. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 28103199	2016
Reply to Liu et al.: Haplotype matters: CD226 polymorphism as a potential trigger for impaired immune regulation in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28137888	2017
Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration. Cell reports\| PubMed ID: 28147279	2017
Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G. Oncoimmunology\| PubMed ID: 28197367	2017
Natalizumab-associated PML: Challenges with incidence, resulting risk, and risk stratification. Neurology\| PubMed ID: 28228564	2017
Animal models in idiopathic inflammatory myopathies: How to overcome a translational roadblock? Autoimmunity reviews\| PubMed ID: 28286105	2017
Targeting Different Monocyte/Macrophage Subsets Has No Impact on Outcome in Experimental Stroke. Stroke\| PubMed ID: 28292872	2017