Journal
/
/
Reconstruction of 3-Dimensional Histology Volume and its Application to Study Mouse Mammary Glands
JoVE Journal
Biology
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Biology
Reconstruction of 3-Dimensional Histology Volume and its Application to Study Mouse Mammary Glands
DOI:

10:59 min

July 26, 2014

, , , , , , ,

Chapters

  • 00:05Title
  • 01:56Histology and Blockface Imaging
  • 04:21Image Registration
  • 08:37Comparing Reconstructed Mammary Tissue in WT and IGFBP7-Null Mice
  • 10:10Conclusion

Summary

Automatic Translation

We present an image registration approach for 3-dimensional (3D) histology volume reconstruction, which facilitates the study of the changes of an organ at the level of macrostructures made up of cells . Using this approach, we studied the 3D changes between wild-type and Igfbp7-null mammary glands.

Related Videos

Read Article