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Neuroscience

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Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo
 

Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo

Article DOI: 10.3791/51473
March 29th, 2014

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Summary March 29th, 2014

GABAergic presynaptic inhibition is a powerful inhibitory mechanism in the spinal cord important for motor and sensory signal integration in spinal cord networks. Underlying primary afferent depolarization can be measured by recording of dorsal root potentials (DRP). Here we demonstrate a method of in vivo recording of DRP in mice.

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