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JoVE Journal
Immunology and Infection

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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
 

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Article doi: 10.3791/51556
August 8th, 2014

Summary August 8th, 2014

Animal models have proven to be invaluable tools in defining host and pathogen specific mechanisms that contribute to the development of chronic inflammation. Here we describe a mouse model of oral infection with the human pathogen Porphyromonas gingivalis and detail methodologies to assess the progression of inflammation at local and systemic sites.

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