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Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation
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Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation

Article DOI: 10.3791/51695
July 23rd, 2014 •
1, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1,3
1Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 2Cardiothoracic Surgery, Nationwide Children's Hospital, 3Pediatric Surgery, Nationwide Children's Hospital

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July 23rd, 2014

In order to understand the cellular and molecular mechanisms underlying neotissue formation and stenosis development in tissue engineered heart valves, a murine model of heterotopic heart valve transplantation was developed. A pulmonary heart valve was transplanted to recipient using the heterotopic heart transplantation technique.

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