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JoVE Journal
Neuroscience

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JoVE Journal Neuroscience
Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line
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Journal (Neuroscience)
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Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line

Article DOI: 10.3791/51748
August 9th, 2014 •
1, 1, 1
1University Clinics for Child and Adolescent Psychiatry, University of Zürich

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August 9th, 2014

Improved in vitro neurotoxicity assays would aid the identification of new neuroprotective compounds. The utility of a real-time impedance-based cell analyzer to determine cytotoxicity and cytoprotection in neuronal cell lines and to delineate the involvement of second messenger pathways, thus gaining insight in the mechanism of neuroprotection is presented.

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