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JoVE Journal
Bioengineering

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Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins
 

Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins

Article doi: 10.3791/51789
August 7th, 2014 Usage Statistics

Summary August 7th, 2014

Several pathological biomarkers cannot be easily detected by current techniques because of their low concentration in biological fluids, the presence of degrading enzymes, and large amounts of high molecular weight proteins. Chemically functionalized hydrogel nanoparticles can harvest, preserve and concentrate low abundance proteins enabling the detection of previously undetectable biomarkers.

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