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JoVE Journal Engineering
Sammenhængende anti-Stokes Raman spredning (CARS) Mikroskopi visualiserer farmaceutiske tabletter under opløsning
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Sammenhængende anti-Stokes Raman spredning (CARS) Mikroskopi visualiserer farmaceutiske tabletter under opløsning

Article DOI: 10.3791/51847-v • 09:59 min • July 4th, 2014
July 4th, 2014 •
1, 2, 1, 3, 1
1Optical Sciences Group, MESA+ Institute, University of Twente, 2Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine University, 3Division of Pharmaceutical Technology, Faculty of Pharmacy, University of Helsinki

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Sammenhængende anti-Stokes Raman spredning (CARS) mikroskopi kombineres med en iboende gennemstrømning opløsning setup til at tillade in situ og real-time visualisering af overfladen af farmaceutiske tabletter gennemgår opløsning. Ved hjælp af denne specialbygget setup, er det muligt at korrelere CARS videoer med narkotika opløsningsprofiler optaget ved hjælp af inline UV-absorption spektroskopi.

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Fysik Sammenhængende anti-Stokes Raman spredning mikroskopi farmaci opløsning, theophyllin tablet
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