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Coerentes anti-Stokes Raman Scattering (CARS) Microscopia visualiza farmacêuticas Comprimidos durante a dissolução
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Coerentes anti-Stokes Raman Scattering (CARS) Microscopia visualiza farmacêuticas Comprimidos durante a dissolução

Article DOI: 10.3791/51847-v • 09:59 min • July 4th, 2014
July 4th, 2014 •
1, 2, 1, 3, 1
1Optical Sciences Group, MESA+ Institute, University of Twente, 2Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine University, 3Division of Pharmaceutical Technology, Faculty of Pharmacy, University of Helsinki

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Microscopia de coerência de anti-Stokes Raman (CARS) é combinado com uma instalação de dissolução intrínseca de fluxo para permitir a visualização in situ e em tempo real da superfície de comprimidos farmacêuticos submetidos a dissolução. Usando esta configuração custom-built, é possível correlacionar CARROS vídeos com perfis de dissolução de medicamentos registrados usando espectroscopia de absorção UV embutida.

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Física Edição 89 Coherent espalhamento anti-Stokes Raman microscopia farmacêutica dissolução, teofilina tablet
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