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The Attentional Set Shifting Task
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The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice

Article DOI: 10.3791/51944 • 09:15 min • February 4th, 2015
February 4th, 2015 •
1, 1, 1, 1, 1, 1,2
1Department of Pharmacology, University of Texas Health Science Center at San Antonio, 2Audie L. Murphy VA Hospital, South Texas Veteran's Health Care System

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Summary
Automatic Translation

The goal of this protocol is to perform a behavioral assay such as the attentional set shifting task (AST) to assess prefrontal cortex-mediated cognitive flexibility in mice.

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Attentional Set Shifting Task Cognitive Flexibility Mice Cognitive Impairment Prefrontal Cortex Dysfunction Neuropsychiatric Disorders Neurodevelopmental Disorders Depression Post-traumatic Stress Disorder Schizophrenia Autism Spectrum Disorder Cognitive Function Deficits Serotonin Reuptake Inhibitors Tricyclic Antidepressants Functional Neuroimaging Studies Postmortem Analysis Human Brain Tissue Preclinical Behavioral Assays Mouse Models Genetic Manipulation Treatment Avenues Attentional Set Shifting Task Adaptation Prefrontal Cortex Mediated Cognitive Deficits Neural Circuits
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