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Neuroscience

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JoVE Journal Neuroscience
The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures
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The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures

Article DOI: 10.3791/52023
October 23rd, 2014 •
1, 2, 1
1Anatomical Institute, Department of Biomedicine Basel, University of Basel, 2Department of Neonatology, University Children's Hospital (UKBB), University of Basel

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October 23rd, 2014

A protocol for entorhino-hippocampal organotypic slice cultures, which allows reproducing many aspects of ischemic brain injury, is presented. By studying changes of the neurovasculature in addition to changes in the neurons, this protocol is a versatile tool to study plastic changes in neural tissue after injury.

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