Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Caitlin L. Carew; Erica L. Tatham; Andrea M. Milne; Glenda M. MacQueen; Geoffrey B.C. Hall

doi:10.3791/52061

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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

JoVE Journal
Behavior

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JoVE Journal Behavior

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

10,378 Views

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08:42 min

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May 19, 2015

DOI:

10.3791/52061-v

DOI:

10.3791/52061-v

•

08:42 min

May 19, 2015

•

2 Views

Caitlin L. Carew¹, Erica L. Tatham², Andrea M. Milne¹, Glenda M. MacQueen³, Geoffrey B.C. Hall⁴

¹Department of Psychiatry and Behavioural Neurosciences,McMaster University, ²McMaster Integrative Neuroscience Discovery and Study,McMaster University, ³Department of Psychiatry,University of Calgary, ⁴Department of Psychology, Neuroscience & Behaviour,McMaster University

Summary

We aim to identify the neural correlates underlying sustained and transient thought suppression, and thought re-emergence in controls, at-risk and depressed individuals. Activation was greatest for controls compared to the at-risk and the depressed group in the dorsolateral prefrontal cortex during thought suppression and anterior cingulate cortex during thought re-emergence.