The MATLAB-based, open source software package, plusTipTracker, can be used to analyze image series of fluorescently-labeled +TIPs to quantify microtubule dynamics.
Stout, A., D'Amico, S., Enzenbacher, T., Ebbert, P., Lowery, L. A. Using plusTipTracker Software to Measure Microtubule Dynamics in Xenopus laevis Growth Cones. J. Vis. Exp. (91), e52138, doi:10.3791/52138 (2014).