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Journal / Immunology and Infection / 在乳腺癌检测人类白细胞抗原生物标志物的利用无标记生物传感技术…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
在乳腺癌检测人类白细胞抗原生物标志物的利用无标记生物传感技术
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在乳腺癌检测人类白细胞抗原生物标志物的利用无标记生物传感技术

Article DOI: 10.3791/52159-v • 08:27 min • March 24th, 2015
March 24th, 2015 •
1, 1, 1, 1, 1, 2, 2, 2,3, 1
1Experimmune, A Center for Immunotherapeutic Development, Department of Immunotherapeutics and Biotechnology, Texas Tech University Health Sciences Center, 2Resonant Sensors Incorporated, 3University of Texas Arlington

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完整的I类HLA /肽复合物是由肿瘤细胞脱落，代表了潜在的癌症相关的生物标志物。利用无标记传感器技术和T细胞受体的模仿的单克隆抗体，检测棚-MIF / HLA-A *的02：01配合在MDA-MB-231细胞上清液，掺入人血清，并且患者血浆证明，有利的发展一种新型癌症诊断平​​台。

Tags

免疫学，第97，HLA，生物标志物，乳腺癌，TCRM，诊断，无标记，单克隆抗体
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