/
/
3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 02:10Analysis of Periventricular Cellular Integrity and 3D Modeling of the Mouse Lateral Ventricle
- 06:24Modeling the Human Lateral Ventricle Using MRI Data
- 09:06Longitudinal Representation of Lateral Ventricles from MRI Data
- 10:40Human Periventricular Tissue Preparation and Analysis
- 12:59Results: 3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans
- 14:41Conclusion
Using MRI scans (human), 3D imaging software, and immunohistological analysis, we document changes to the brain’s lateral ventricles. Longitudinal 3D mapping of lateral ventricle volume changes and characterization of periventricular cellular changes that occur in the human brain due to aging or disease are then modeled in mice.
