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Chapters
- 00:05Title
- 02:02Pre-clinical Trial in an Epithelial Damage and Acute Colitis Model
- 04:32Endoscope Examinations
- 07:24Results: Acute DSS-induced Mucosal Damage
- 08:25Conclusion
We describe methods for longitudinal monitoring of the efficacy of therapeutics for the treatment of colonic pathologies in mice using a rigid endoscope. This protocol can be readily used for the characterization of the therapeutic response of an individual tumor in live mice and also for monitoring potential disease relapse.
Tags
Keywords: Non-invasive AssessmentTherapeutic EfficacyIntestinal PathologiesEndoscopic ImagingLive MiceAnimal ModelsInflammatory Bowel DiseaseColorectal CancerPre-clinical StudiesAcute Mucosal DamageChronic ColitisColitis-associated Colon CancerSporadic Colorectal CancerSerial Endoscopic ExaminationTherapeutic ResponseHealth Monitoring
