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JoVE Journal
Bioengineering

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Detection of Exosomal Biomarker by Electric Field-induced Release and Measurement (EFIRM)
 

Detection of Exosomal Biomarker by Electric Field-induced Release and Measurement (EFIRM)

Article DOI: 10.3791/52439 11:02 min
January 23rd, 2015

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Summary January 23rd, 2015

Exosomes are microvesicular structures found within biofluids that potentially carry important disease discriminatory biomarkers. Here, a novel method is used to specifically extract exosomes and rapidly test the exosomal cargo for both RNA/protein targets following the disruption of exosomes using non-uniform electric cyclic square waves.

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