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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
JoVE Journal
Medicine
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JoVE Journal Medicine
A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
DOI:

14:05 min

December 20, 2014

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Chapters

  • 00:00Title
  • 02:22Surgical Preparation
  • 03:40Unilateral Ureteric Obstruction
  • 04:33Preparation for Reversible Unilateral Ureteric Obstruction
  • 06:20Post-operative Care
  • 06:58Reversible Unilateral Ureteric Obstruction
  • 11:39Representative Results
  • 13:04Conclusion

Summary

Automatic Translation

The murine model of irreversible unilateral ureteric obstruction (UUO) is presented together with the model of reversible UUO in which the ureteric obstruction is relieved by anastomosis of the severed ureter into the bladder. These models enable the study of renal inflammation and scarring as well as tissue remodeling.

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