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JoVE Journal
Neuroscience

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Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array
 

Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array

Article DOI: 10.3791/52601
March 27th, 2015

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Summary March 27th, 2015

We have developed an in vitro unfolded hippocampus which preserves CA1-CA3 array of neurons. Combined with the penetrating micro-electrode array, neural activity can be monitored in both the longitudinal and transverse orientations. This method provides advantages over hippocampal slice preparations as the propagation in the entire hippocampus can be recorded simultaneously.

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